The Pip-Boy frames feature more realistic artwork as though the games might show you through the lens of your Pip-Boy 3000
There's a good bit of variety among the ones revealed so far, from the aggressive but elusive Elsa - The Fifth Spirit to the singing bodyguard Kristoff - Reindeer Keeper
The white card you find, for example, can be any number of colors, as long as white is one of them
The chase cards in the set proper start with the crime family triomes, like Jetmir's Garden or Spara's Headquarters
The Wurmwall Sweeper, for example, needs to be crewed by four or more, so using Station to put a couple of 2/2s in there would work nicely
If you had the mana to play him and wanted a large creature that didn't need to kill your opponent on the spot, you played it, period