A little pricey, at 4 mana if it's not making you win the game, but it's potentially devastating, and can also be part of a "coming and going" strategy where you have multiple triggers when creatures or tokens come into play and are destroyed or sacrificed, which I like to do
Magmatic Galleon, Chandra's Incinerator, and Virtue of Courage are just a few examples
Learn more: Tomb of Annihilation Asmodeus the Archfiend Asmodeus, the Lord of the Nine Hells, wants to rule the cosmos
Lets add both Helm of the Gods and Swiftfoot Boots
Plus, you can add in unblockable infrastructure you likely already have in the deck to win
Here are a list of the other life gain cards that see a decent amount of cube play that didn't quite make the top ten