The big drawback when playing this deck is its inconsistency
Once those all-powerful cards are in play, it's time to make sure they stay there
When Red is trying to do something, it will do so quickly, or die trying
By using cantrip and draw effects as well as mana generation cards like Dark Ritual, Black Lotus, and others, it's easy to instantly kill a player without them ever having had a turn
If Minwu or another Cleric you control is dealt lethal damage at the same time that you gain life, it will die before Minwu's last ability would resolve
Common situations are stopping a Jace, Vryns Prodigy from flipping, putting your opponent in a spot where they have to choose between removal for the other thing you played or reestablishing a board, removing the thing they were using as a good blocker, or just generally when they have something that they want to recast that costs three or more