Us old timers might have forgotten that it's weird that U means blue, but I know it throws new players for a loop the first time they see it
Then, once you hit 25 or more life, Angel of Vitality gets a bonus +2/+2, turning her into a 4/4 with flying, which can take down your opponent in just a few short turns
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It's more ideal to not have your battlefield broken, but rebuilding it's the hardest, but can leave your defenses open.
Heliod, the Radiant Dawn is a very straightforward commander in this way, costing a fairly cheap four mana to transform him, or three mana and two life, to compleat the poor god, turning him into a twisted, Phyrexianized version of himself