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Cell Reports 2021
With a peak absorption at 584 nm
DOTA bifucational chelator containing a carboxylic acid group
Product Name Lenalidomide-PEG5-OH Synonyms Lenalidomide-4'-PEG5-OH CAS Number n/a Related CAS Molecular Formula C23H33N3O8 Molecular Weight 479
Product Name DOTA-tris(t-Bu)ester-C4-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C39H67N7O10 Molecular Weight 794
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-PNP m-peg8-pab Cell Reports 2021SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating
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