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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan clip Product Name DOTA-PEG4-C2-amine Synonyms CAS

SKU: 88907955433

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Description

Product Name DOTA-PEG4-C2-amine Synonyms CAS Number 2090232-34-9 Related CAS Molecular Formula C26H50N6O11 Molecular Weight 622

[O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

providing flexibility in protein labeling and tracking

527 SMILES [N-]=[N+]=NCCOCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

exhibited longer fluorescence lifetimes than its non-sulfonated counterparts

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan clip Product Name DOTA-PEG4-C2-amine Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent

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