The same is true for opus (Prismari) and increment (Quandrix), which don't require a lot of effort to work, while infusion and the Lorehold card need some more dedication (but the latter triggers over flashback cards, which are usually good by themselves)
But giving the Chimera away doesnt end the subgame
Liesa, Forgotten Archangel Next is the newer (albeit weaker) version of Liesa, Liesa, Forgotten Archangel
So, even if you draw a card to answer the big threat that came out of your deck, you'll likely have to discard it before you can use it
Additionally, theres the issue that there simply may not be someone within your area that wants a card
Experimental Augury I love that proliferate is attached to so many cards as extra flavor