Skeletal Swarming Look, I'm not going to turn down the opportunity to turn the game into a bone-themed mosh pit
You really want the creatures that will immediately give you a ton of value, even if your opponent has something like Swords to Plowshares, so ideally, you pick up Atraxa, Archon, and Griselbrand
Slowly build up your boardstate with your opponent's cards, then when you have assessed your grand heist, turn all that wealth into a game win
For a two-mana walker, that kind of long-term control is honestly a little rude but it is also exactly what makes Wrenn and Six one of the best planeswalkers in MTG
Getting behind on the number of cards in your hand is just as bad maybe worse, in fact than getting behind in ink
However, if the opponent challenges one of the player's cards while Musketeer is in play, that challenger must also have the "Bodyguard" trait