The answer to this question can vary quite a bit, depending on your decks focus and underlying strategies
Even at just 2 mana, direct burn is direct burn, and since this can hit any target, it can also get rid of a Planeswalker in a pinch
Lorcana, with its mix of recognizable as well as unexpected characters and objects Anna and Elsa from Frozen will duke it out with Sergeant Tibbs from 101 Dalmatians and all eras of Mickey Mouse aims to play with our nostalgia as much as it does game mechanics, as cards will reference signature Disney weapons (a frying pan) with recognizable songs (Hakuna Matata, Friends on the Other Side)
Ygra, Eater of All is an interesting sacrifice enabler, in that it makes all creatures Food, so any player can sacrifice a creature and gain life
You can still run cards like Collector Ouphe or Spirit of the Labyrinth, though youll need to keep non-human or angel creatures to a minimum
Always assume people are playing graveyard hate and learn what does and doesnt work in your deck to circumvent it