Youve got tech, mutants, radiation effects, and characters like Dr
The dream is playing this on turn 2 as a Rampant Growth effect, and that will come up occasionally, but as the Nurturing Pixie decks have shown us, just being able to bounce a creature back to your hand to reset an Enters ability can be good enough
Since most critter tokens are 2 or fewer toughness, you can sweep them all in one fell swoop
mana to kill a small-medium creature is fine, as is destroying an artifact
Grind is a nice way to put out -1/-1 counters, and the aftermath of Dust makes a huge impact if you spread around three or more negative counters
Auction house PWCC, which sold the expensive card, claims that the sum makes Lord of the Pit the second-most valuable MTG card after Black Lotus