Use efficient removal I feel bad saying something so obvious, but in a metagame dominated by Decay and Lilly, as well as decks that don't want to interact at all, Infect has a huge edge
Her power is our total dork's total and then a nice 4 toughness
This makes market evaluation completely unpredictable
It's also not uncommon to be attempting to win the game outright the turn after you land a Smothering TitheSmothering Tithe or a BurgeoningBurgeoning with some sort of "draw when your opponents draw" trigger
Nevertheless, the idea of taking extra turns has always been an attractive one for Magic designers and players
My personal favorite was Malignant Growth, a much maligned Blue/Green Enchantment that was interesting, to say the least, especially in melee games