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MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-free assay
Sidearm tubulations are 8mm O
showing no activity at other mGlu subtypes
used as an anticoagulant
and exhibits anti-inflammatory
Boceprevir 3.0 MK-8776 (SCH 900776) is aBoceprevir is an oral, direct acting hepatitis C virus (HCV) protease inhibitor with Ki value of 14 nM for NS3. It is used in combination with other antiviral agents in the treatment of chronic hepatitis C, genotype 1.
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